Acme Oyster House brings the taste of New Orleans to the heart of Destin with its famous oysters, Cajun classics, and festive atmosphere. Founded in 1910 in the French Quarter, Acme has grown into a Gulf Coast legend—known for its fresh shucked oysters, seafood platters, and signature po’boys served with southern charm and a side of good times.
The Destin Harbor location captures everything that makes Acme iconic: lively energy, waterfront views, and bold Louisiana flavors. Guests can enjoy chargrilled oysters sizzling straight off the grill, gumbo packed with rich Cajun spice, or a classic shrimp po’boy paired with a cold beer from the bar. The menu celebrates Gulf seafood at its best, with every bite bringing a little bit of Bourbon Street to the Emerald Coast.
Families, groups, and oyster lovers alike flock to Acme for its upbeat atmosphere and friendly service. Whether you’re sitting inside surrounded by neon lights and laughter or on the patio watching boats glide through the harbor, Acme offers an unforgettable experience that’s equal parts dining and celebration.
From its roots in New Orleans to its home on Destin Harbor, Acme Oyster House delivers a true taste of the Gulf—fresh, flavorful, and full of character. For those craving seafood with soul, this is where every meal feels like Mardi Gras.
